Five human tumor cell lines were treated in vitro with extract from the embryos of Zebrafish (glioblastoma, melanoma, adenocarcinoma of the kidney, lung and of the lymphoblastic leukemia).
Each line has demonstrated a reduction of cell growth resulting from the treatment with Zebrafish embryonic extracts.
This extract was taken from embryos during the stages of cell differentiation. If you extract during the mere embryonic growth phase you don’t get any reduction.
These results suggest that during the differentiation steps there are factors that control the growth of cancer cells and that they can be used in therapy.
On the other hand, it is known that stem cells can be differentiated in various ways and it is in this way that they produce the various types of tissues guided by factors present in the embryonic environment.
These cellular differentiation factors can normalize the expression of the genes and it is therefore conceivable that they can represent a gene therapy.
It is suggested to add to all the surgical therapies the treatment with factors of differentiation of stem cells that stop the maturation toward malignancy of cells that can give rise to the tumor.